FIGURE

Fig. 5

ID

ZDB-FIG-110531-5

Publication

Mapp et al., 2011 - Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity

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Fig. 5

REST function is required for FBMN migration. (A-C) Maximum projection dorsal views of FBMNs (green) in 42 hpf Tg(islet1:GFP) zebrafish embryos, immunostained for EphA4 to mark r5 (red). FBMN migration is partially disrupted in REST morphants (B) and in mCherry-zhREST4-injected embryos (C), relative to controls (A). Scale bar: 20 μm. (D) The extent of FBMN migration was scored in embryos with disrupted REST function. The number of embryos scored is indicated in parentheses.

Expression Data

Genes:	epha4a GFP
Fish:	rw0Tg rw0Tg + MO1-rest
Knockdown Reagent:	MO1-rest
Anatomical Terms:	facial nerve motor nucleus motor neuron rhombomere 5
Stage:	High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rw0Tg + MO1-rest
Knockdown Reagent:	MO1-rest
Observed In:	facial nerve motor nucleus neuron migration
Stage:	High-pec

Phenotype Detail

Acknowledgments

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