FIGURE

Fig. 5

ID
ZDB-FIG-101118-31
Publication
Song et al., 2010 - Neural and Synaptic Defects in slytherin, a Zebrafish Model for Human Congenital Disorders of Glycosylation
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Fig. 5

A–C. mib excludes srn phenotypes. A. AAL staining is reduced in srn and srn + mib double mutants, but not in mib. B. srn + mib double mutants showed reduction of secondary motor neurons, more severe than srn but similar to mib alone. C. srn + mib double mutants have reduced GFAP+ glia, more severe than srn, but similar to mib alone (15 embryos, 2 carrier pairs for each). Scale bar = 40 μm. D–F. DAPT treatment excludes srn phenotypes. D. AAL staining is reduced in srn and srn mutants treated with DAPT, but not in DAPT treated embryos. E. srn mutants treated with DAPT showed reduction of secondary motor neurons, more severe than srn but similar to DAPT treated embryos. F. srn mutants treated with DAPT showed reduction of GFAP+ glia, more severe than srn, but similar to DAPT treated WT embryos (10 embryos, 2 carrier pairs for each). Scale bar = 40 μm.

Expression Data
Antibody:
Fish:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
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