FIGURE

Fig. 3

ID

ZDB-FIG-101105-38

Publication

Jurynec et al., 2010 - SHIP2, a factor associated with diet-induced obesity and insulin sensitivity, attenuates FGF signaling in vivo

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Fig. 3

Knockdown of maternal Ship2a alters BMP but not WNT signaling pathways. (A-D) Expression of bmp7 is reduced in 30-40% epiboly and 50% epiboly maternal ship2a morphants as compared with WT controls. (E-J) Gene expression that is dependent on the WNT signaling pathway is not affected in maternal ship2a-morphant embryos. Expression of vox (E,F) or vent (G,H) in 40% epiboly embryos, or bozozok (boz) (I-J) in oblong stage (3.7 hpf) embryos, is unchanged by depletion of maternal Ship2a. A?H, animal pole views with dorsal to the right; I and J, lateral views with animal pole up and dorsal to the right.

Expression Data

Genes:	bmp7a dharma vent vox
Fish:	AB AB + MO1-inppl1a
Knockdown Reagent:	MO1-inppl1a
Anatomical Terms:	blastoderm blastoderm ventral region blastodisc dorsal region
Stage Range:	Oblong to 50%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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