FIGURE

Fig. 8

ID

ZDB-FIG-100211-11

Publication

Chuang et al., 2010 - The zebrafish homeobox gene irxl1 is required for brain and pharyngeal arch morphogenesis

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Fig. 8

The arch cartilage patterning is disrupted in irxl1 morphants. Cartilage elements were stained with Alcian blue at 5 dpf. A-E: Lateral views. F-J: Ventral views. A,F: Wild-type. B-D,G-I: Morphants of MOI (0.5 pmol plus 0.75 pmol p53 MO) and MOII (0.5 pmol) exhibiting different degrees of cartilage defects are shown as indicated. E,J: MOII morphants rescued by co-injection of irxl1(a+b) cRNA. Arrows indicate the malformed ch (B,I) and pq (H) cartilages; double arrows (H) indicate an increased angle between the ceratohyal cartilages. bb, basibranchials; cb, ceratobranchials; ch, ceratohyal; hys, hyosymplectic; m, Meckel′s cartilage; pq, palatoquadrate. Scale bar = 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-mkxa + MO4-tp53 WT + MO2-mkxa
Knockdown Reagents:	MO1-mkxa MO2-mkxa MO4-tp53
Observed In:	ceratobranchial cartilage ceratohyal cartilage embryonic viscerocranium morphogenesis Meckel's cartilage palatoquadrate cartilage
Stage:	Day 5

Phenotype Detail

Acknowledgments

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