FIGURE

Fig. 2

ID

ZDB-FIG-090804-69

Publication

Dodd et al., 2009 - The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

hi1520 mutant phenotypes at 48 hpf. (A-C′) Wild-type (A-C) and clint1 mutant (A′-C′) 48 hpf zebrafish embryos labeled for BrdU incorporation (green) and p63 (red) (A,A′), Acridine Orange (AO) (B,B′) or Mpo (green) and BrdU incorporation (red) (C,C′). Boxed region, caudal hematopoietic tissue (CHT). Arrowheads identify proliferation in p63-positive (yellow arrowheads) and p63-negative (white arrowheads) cells (A′,C′), and cell death (B′) in clint1 mutants. Arrows identify epidermal aggregates (A′) and neutrophils (C′) in clint1 mutants. Yellow arrow (C′) identifies a proliferating neutrophil. (D-F) Quantification of BrdU (D) and AO (E) in fin fold and overall displacement of neutrophils (F) in wild-type (circles) and clint1 mutant (triangles) embryos. Bars represent the mean. Scale bars: 200 μm.

Expression Data

Genes:	mpx tp63
Antibodies:	Ab1-mpx Ab1-tp63
Fish:	AB clint1a^{hi1520Tg/hi1520Tg} (AB)
Anatomical Terms:	epidermis hematopoietic system neutrophil ventral fin fold neutrophil
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	clint1a^{hi1520Tg/hi1520Tg} (AB)
Observed In:	cell death epithelial cell proliferation inflammatory response leukocyte migration involved in inflammatory response ventral fin fold neutrophil
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development