FIGURE

Fig. 8

ID

ZDB-FIG-090804-75

Publication

Dodd et al., 2009 - The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

Mesenchymal behavior of epidermal cells in clint1 mutants. (A,B) Still images from in vivo time-lapse microscopy of keratinocyte clusters from uninjected (A) (see Movie 5 in the supplementary material) or clint1-ex1 MO-injected (B) (see Movie 6 in the supplementary material) Tg(β-actin:hras-eGFP) zebrafish embryos that were transplanted into ventral ectoderm of non-transgenic wild-type (A) or clint1 morphant (B) embryos, respectively. Epidermal cells from clint1 morphants exhibit loss of cell-cell contacts and increased motility (B,D). Note the change in position of the numbered cells in B. (C,D) Quantification of migration of the numbered GFP-positive keratinocytes in unlabeled wild type (C) (see Movie 5 in the supplementary material) or clint1-morphant recipients (D) (see Movie 6 in the supplementary material). Scale bar: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development