FIGURE

Fig. 6

ID

ZDB-FIG-090804-6

Publication

Kurrasch et al., 2009 - Neuroendocrine transcriptional programs adapt dynamically to the supply and demand for neuropeptides as revealed in NSF mutant zebrafish

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Fig. 6

Injection of botulinum toxin B into wild-type zebrafish mimics the nsf^st53phenotype. Whole-mount in situ hybridization for wild-type (WT) and WT + botox at 5 dpf is shown (n = 4 each). The expression of neuroendocrine markers in botox-injected WT fish is highlighted (black arrowheads). Relative transcript levels are shown for the heads of WT and WT + botox at 5 dpf (n = 8 each). Fold induction is relative to one control sample and taken to be 1.0. All other samples, including additional control and experimental samples, are normalized to this one wild-type sample. Sample variation is shown by error bars (standard error of the mean). Statistical analyses were done by unpaired t-test. *P < 0.05; **P < 0.01. NS = not significant.

Expression Data

Genes:	avp crhb hcrt nr5a1b oxt
Fish:	WT
Condition:	chemical treatment: toxin
Anatomical Term:	hypothalamus
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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