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General Information
ZIRC
ZFIN ID: ZDB-GENE-030407-2
Gene Name: arginine vasopressin
Gene Symbol: avp    Nomenclature History

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Previous Names: arginine vasotocin (1), avpl (1), AVT (1), vasotocin neurophysin (1), vsnp, VT-NP (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have neuropeptide hormone activity. Localizes to the axon hillock. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Is expressed in nervous system. Orthologous to several human genes including AVP (arginine vasopressin).
Genome Resources: Alliance (1),  Gene:352922 (1),  Ensembl(GRCz11):ENSDARG00000058567 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-avp N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH avp HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neurohypophyseal diabetes insipidus Alliance Diabetes insipidus, neurohypophyseal 125700
DISEASE ASSOCIATED WITH avp VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component axon hillock (more)
Molecular Function neurohypophyseal hormone activity (more)
GO Terms (all 7)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA avp-201 (1)    Ensembl 517
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-avp polyclonal Rabbit IHC 2
Ab2-avp polyclonal Rabbit IHC Bachem
3
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM avp
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
TgBAC(avp:KALTA4) avp KALTA4 Danio rerio 1 2
MARKER RELATIONSHIPS
avp Contained in: [BAC] CH73-129K1 (1) (order this)
avp Encodes: [EST] fj35h07
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_178293 (1) 540 bp
Genomic GenBank:CU896541 (1) 104170 bp
Select Tool
Polypeptide UniProtKB:F8W5D0 (1) 151 aa
Sequence Clusters UniGene:20033 (1)
Sequence Information (all 10)
ORTHOLOGY for avp ( Chr: 8 )
CITATIONS (50)