FIGURE

Fig. 8

ID

ZDB-FIG-090331-14

Publication

Nelson et al., 2009 - Retinal homeobox 1 is required for retinal neurogenesis and photoreceptor differentiation in embryonic zebrafish

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Fig. 8

Temporally-selective rx1 depletion results in a reduction in the expression of rod and cone opsins and rod and cone transducins. Embryos were injected with the 5-mispair control MO (A, C, E, G, I, K) or an rx1-targeting MO cocktail (B, D, F, H, J, L) and were processed as whole mounts for in situ hybridization with cRNA probes corresponding to red cone opsin (A, B), rod opsin (C, D), blue cone opsin (E, F), rod transducin alpha subunit (gnat1; G, H), UV cone opsin (I, J), or cone transducin alpha subunit (gnat2; K, L). Scale bar = 50 μm.

Expression Data

Genes:	gnat1 gnat2 opn1lw1 opn1sw1 opn1sw2 rho
Fish:	WT WT + MO2-rx1 + MO3-rx1
Knockdown Reagents:	MO2-rx1 MO3-rx1
Anatomical Term:	retina
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 328(1), Nelson, S.M., Park, L., and Stenkamp, D.L., Retinal homeobox 1 is required for retinal neurogenesis and photoreceptor differentiation in embryonic zebrafish, 24-39, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.