Fig. 1
Sequence comparison and in situ expression analysis of zebrafish gpr161. (A) Genbank accession no. of human GPR161: NM_007369 (Homo); zebrafish gpr161: EU090912 (Danio). 7TM (black), DRY (red) and PxxY (red) motifs were boxed. (B) gpr161 expression in the developing embryos by whole mount in situ hybridization. Inset showed the expression in developing somites and expression surrounding the Kupffer's vesicle (KV) near the tail bud region at 9-somite stage. All scale bars were 100 μm. |
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Stage Range: | 5-9 somites to 14-19 somites |
Reprinted from Developmental Biology, 323(1), Leung, T., Humbert, J.E., Stauffer, A.M., Giger, K.E., Chen, H., Tsai, H.J., Wang, C., Mirshahi, T., and Robishaw, J.D., The orphan G protein-coupled receptor 161 is required for left-right patterning, 31-40, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.