Gene
gpr161b
- ID
- ZDB-GENE-030616-58
- Name
- G protein-coupled receptor 161b
- Symbol
- gpr161b Nomenclature History
- Previous Names
-
- gpr161 (1)
- gpr161a
- si:bz20i5.4
- si:rp71-20i5.4
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Acts upstream of or within determination of left/right symmetry and regulation of calcium ion transport. Predicted to be located in cilium. Predicted to be active in plasma membrane and recycling endosome. Is expressed in several structures, including brain; fin bud; liver; mesoderm; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in medulloblastoma. Orthologous to human GPR161 (G protein-coupled receptor 161).
- Genome Resources
- Note
-
novel protein similar to human G-protein coupled receptor RE2
- Comparative Information
-
- All Expression Data
- 19 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2433 (17 images)
- eu1115 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Leung et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| medulloblastoma | Alliance | {Medulloblastoma predisposition syndrome} | 155255 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|
|
UniProtKB:Q90X46
|
526 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gpr161-201
(1)
|
Ensembl | 2,354 nt | ||
| mRNA |
gpr161-202
(1)
|
Ensembl | 1,702 nt |
Interactions and Pathways
No data available
Plasmids
No data available