FIGURE

Fig. 2

ID

ZDB-FIG-081010-9

Publication

Gansner et al., 2008 - Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis

Other Figures

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Fig. 2

The pfd^gw1 mutation disrupts venous plexus and axial vessel formation. A-D: pfd^gw1 was crossed into a fli1:EGFP transgenic line to allow visualization of endothelial cells. A: The caudal vein of wild-type embryos has a well-formed venous plexus (arrowheads). B: The caudal vein of pfd^gw1 mutants has lost its characteristic reticular pattern, and endothelial cells are disorganized (arrowheads). C,D: Dorsal aorta (upper circle) and cardinal vein (lower circle) in a wild-type embryo (C) and a pfd^gw1 mutant (D) demonstrating reduced axial vessel diameters in the mutant (D, circles). Embryos were photographed at 30 hours postfertilization (hpf; C,D) and 35 hpf (A,B).

Expression Data

Gene:	EGFP
Fish:	y1Tg fbn2b^gw1/gw1; y1Tg
Anatomical Terms:	blood vessel endothelial cell caudal vein plexus dorsal aorta posterior cardinal vein
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fbn2b^gw1/gw1; y1Tg
Observed In:	blood vessel development caudal vein caudal vein blood vessel endothelial cell caudal vein plexus dorsal aorta posterior cardinal vein (all 6)
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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