FIGURE

Fig. 5

ID

ZDB-FIG-080828-36

Publication

Honjo et al., 2008 - Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

nrg1 alone is not required for DRG formation. (A) RT-PCR showing expression of each nrg1 isoform at various developmental stages and in the adult brain. (B,D,F) Expression patterns of each isoform at 24 hpf shown in whole-mount. (C,E,G) Cross section of expression pattern of each isoform respectively. (B,C) Type I is expressed weakly in somites. (D,E) Type II and (F,G) type III are expressed strongly in ventral spinal cord neurons. (E,F) Elavl labeling at 2 dpf. (H,I) Control MO-injected embryos (H) had segmental DRG neurons. nrg1 MO-injected embryos (I) had only a slight decreased in DRG neuron number; arrowhead indicates absent DRG, asterisk shows mislocalized DRG. Scale bar: 40 μm.

Expression Data

Gene:	nrg1
Antibody:	Ab1-elavl
Fish:	WT
Anatomical Terms:	brain neuron somite spinal cord whole organism
Stage Range:	50%-epiboly to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-nrg1
Knockdown Reagent:	MO2-nrg1
Observed In:	dorsal root ganglion neuron peripheral nervous system development
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development