FIGURE

Fig. 2

ID

ZDB-FIG-080828-33

Publication

Honjo et al., 2008 - Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons

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Fig. 2

Neural crest cell migration is initially normal but later disrupted in erbb3b mutants. (A-H) Whole-mount labeling using crestin (A,B,E-H) or sox10 (C,D) riboprobes of wild-type embryos (A,C,E,G) and erbb3b mutants (B,D,F,H). At 24 hpf, both probes show that NC cell migration appears normal in erbb3b mutants (B,D) and in wild type (A,C). At 27 (E,F) and 30 (G,H) hpf, NC cells form segmental streams ventral of the notochord in wild type (E,G). By contrast, in erbb3b mutants (F,H) there are no streams at these stages, and NC cell migration is disrupted. Broken lines represent dorsal aspect of the notochord. Lateral views, anterior towards the left. Scale bar: 20 μm.

Expression Data

Genes:	crestin sox10
Fish:	WT erbb3b^st48/st48
Anatomical Term:	neural crest cell
Stage Range:	26+ somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	erbb3b^st48/st48
Observed In:	neural crest cell neural crest cell migration
Stage Range:	26+ somites to Prim-5

Phenotype Detail

Acknowledgments

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