FIGURE
Fig. 5
- ID
- ZDB-FIG-080604-5
- Publication
- Postel et al., 2008 - Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex
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Fig. 5
Plasma membrane retractions of skeletal muscle fibres. (A,B) Double labelling with anti-vinculin antibody (green) and phalloidin (red) in wt sibling embryos (A) and loc/ilk mutant embryos (B) at 4.5 dpf when muscle fibres detach (arrow). Inset shows vinculin staining at the tip of the f-actin filaments (inset in panel B; white arrowheads). (C–K) Double staining for phalloidin (red) and memGFP (green) as separate images or as an overlay taken from a wt embryo (C–E), an itgα7 MO injected embryo (F–H) and an ilk MO injected embryo (I–K) in a region where muscle fibres detached (arrow) at 4.5 dpf. |
Expression Data
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| Knockdown Reagents: | |
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| Stage: | Day 4 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
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| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Day 4 |
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 318(1), Postel, R., Vakeel, P., Topczewski, J., Knöll, R., and Bakkers, J., Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex, 92-101, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.