FIGURE

Fig. 6

ID

ZDB-FIG-080325-11

Publication

Sperber et al., 2008 - Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements

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Fig. 6

Loss of dlx2a but not of dlx1a function perturbs barx1 and goosecoid (gsc) expression in the developing second arch (a2) at 48 hpf. (A, E) Control MO 0.5 mM; (B, F) dlx1aMO 0.5 mM; (C, D) dlx2aMO 0.5 mM; (D, H) dlx1aMO + dlx2aMO 0.25 mM each. (A?D) barx1 expression; arrow indicates the intermediate region. (E?H) gsc expression in lateral views, arrowhead indicates location of the dorsal expression domain in the morphants. a1, first arch; a2, second arch; d, dorsal expression domain; v, ventral expression domain. Scale bar: 50 μm.

Expression Data

Genes:	barx1 gsc
Fish:	WT WT + MO1-dlx1a WT + MO2-dlx2a WT + MO1-dlx1a + MO2-dlx2a
Knockdown Reagents:	MO1-dlx1a MO2-dlx2a
Anatomical Term:	pharyngeal arch 2
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 314(1), Sperber, S.M., Saxena, V., Hatch, G., and Ekker, M., Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements, 59-70, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.