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Fig. 6 Loss of dlx2a but not of dlx1a function perturbs barx1 and goosecoid (gsc) expression in the developing second arch (a2) at 48 hpf. (A, E) Control MO 0.5 mM; (B, F) dlx1aMO 0.5 mM; (C, D) dlx2aMO 0.5 mM; (D, H) dlx1aMO + dlx2aMO 0.25 mM each. (A–D) barx1 expression; arrow indicates the intermediate region. (E–H) gsc expression in lateral views, arrowhead indicates location of the dorsal expression domain in the morphants. a1, first arch; a2, second arch; d, dorsal expression domain; v, ventral expression domain. Scale bar: 50 μm.
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Reprinted from Developmental Biology, 314(1), Sperber, S.M., Saxena, V., Hatch, G., and Ekker, M., Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements, 59-70, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.