FIGURE

Fig. 9

ID

ZDB-FIG-070921-12

Publication

Nambiar et al., 2007 - Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration

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Fig. 9

Wildtype embryos treated late with TSA phenocopy col mutants. Live wildtype embryos at 2 dpf treated with 800 nM TSA late (at 16 hpf) resemble col mutants (A, compare to Fig. 7A). dlx2 expression is unaffected in these embryos (C; *) while the facial hindbrain motorneurons remain in r4 (arrowhead; E) as in col mutants. The position of nV neurons are shown with black arrows. Phenotypes observed at 2 dpf in wildtype embryos treated with 50 nM TSA early (5 hpf) appear more severe (B). The forebrain dlx2 expression domain is reduced (D; *), similar to col mutants, and facial hindbrain motorneurons remain in r4 (F) in these embryos.

Expression Data

Genes:	dlx2a isl1a
Fish:	WT
Condition:	chemical treatment: trichostatin A
Anatomical Terms:	forebrain rhombomere 2 rhombomere 4
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 124(9-10), Nambiar, R.M., Ignatius, M.S., and Henion, P.D., Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration, 682-698, Copyright (2007) with permission from Elsevier. Full text @ Mech. Dev.