FIGURE

Fig. 6

ID

ZDB-FIG-070822-2

Publication

Shi et al., 2006 - Zebrafish foxe3: Roles in ocular lens morphogenesis through interaction with pitx3

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

The foxe3 morphants display reduced eye and pupil size. The foxe3 morphants (panels D-F) are compared to uninjected (panels A–C) and mismatch control morpholino-injected embryos (panels G–I) at 3, 4 and 5 dpf. At 3 dpf, the eyes of the foxe3 morphants (panel D) are slightly reduced in size compared to the controls (panels A and G). At 4 dpf, small pupils also characterize the morphants (compare panel E to panels B and H). The eyes of some morphants lacked a pupillary opening at 5 dpf (compare panel F to panels C and I). The distribution of eye dimensions that were measured along the anterior-posterior axis (length) and dorsal–ventral axis (width) of uninjected control and foxe3 morphants (5 dpf) are shown in panel J. The distributions of control and foxe3 morphant pupil dimensions are also shown (panel K).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-foxe3
Knockdown Reagent:	MO1-foxe3
Observed In:	eye pupil
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 123(10), Shi, X., Luo, Y., Howley, S., Dzialo, A., Foley, S., Hyde, D.R., and Vihtelic, T.S., Zebrafish foxe3: Roles in ocular lens morphogenesis through interaction with pitx3, 761-782, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.