FIGURE

Fig. 1

ID

ZDB-FIG-070802-48

Publication

Gansner et al., 2007 - Essential role of lysyl oxidases in notochord development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

β-Aminopropionitrile recapitulates the notochord phenotype of copper deficiency. Wild-type embryos were incubated in vehicle (A), 10 μM neocuproine (B), or 10 mM β-aminopropionitrile supplemented with 10 �M CuCl₂ (C). At 48 hpf, the notochord (arrowheads) is distorted in embryos treated with neocuproine (B) and β-aminopropionitrile (C); however, melanocytes (arrows) are present after β-aminopropionitrile (C) but not neocuproine treatment (B), demonstrating that β-aminopropionitrile does not act through copper chelation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 307(2), Gansner, J.M., Mendelsohn, B.A., Hultman, K.A., Johnson, S.L., and Gitlin, J.D., Essential role of lysyl oxidases in notochord development, 202-213, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.