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General Information
ZIRC
ZFIN ID: ZDB-FIG-070606-3
Lu et al., 2007 - A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes & Development   21(7):784-796 Full text @ Genes & Dev.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Adult
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Long-pec

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
foxa3 AB control Prim-5 gut ISH
Prim-5 liver primordium ISH
Prim-5 pancreas primordium ISH
Long-pec gut ISH
Long-pec liver ISH
Long-pec pancreas ISH
AB + MO1-ppm1k standard conditions Prim-5 gut ISH
Prim-5 liver primordium ISH
Prim-5 pancreas primordium ISH
Long-pec gut ISH
Long-pec liver ISH
Long-pec pancreas ISH
myh6 AB control Prim-15 heart tube ISH
Long-pec atrium ISH
AB + MO1-ppm1k standard conditions Prim-15 heart tube ISH
Long-pec atrium ISH
myh7 AB control Prim-15 presumptive cardiac ventricle heart tube ISH
Long-pec cardiac ventricle ISH
AB + MO1-ppm1k standard conditions Prim-15 presumptive cardiac ventricle heart tube ISH
Long-pec cardiac ventricle ISH
pax2a AB control Prim-5 midbrain hindbrain boundary ISH
Prim-5 otic vesicle ISH
Prim-5 spinal cord ISH
Long-pec midbrain hindbrain boundary ISH
Long-pec otic vesicle ISH
Long-pec spinal cord ISH
AB + MO2-ppm1k standard conditions Prim-5 midbrain hindbrain boundary ISH
Prim-5 otic vesicle ISH
Prim-5 spinal cord ISH
Long-pec midbrain hindbrain boundary ISH
Long-pec otic vesicle ISH
Long-pec spinal cord ISH
ppm1k AB standard conditions Prim-5 brain ISH
Prim-5 neural tube ISH
Adult brain RTPCR
Adult heart RTPCR
Adult liver RTPCR
Adult trunk musculature RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-ppm1k standard conditions Prim-5 brain malformed, abnormal
Prim-5 brain development disrupted, abnormal
Prim-5 digestive system malformed, abnormal
Prim-5 digestive tract development disrupted, abnormal
Prim-5 gut malformed, abnormal
Prim-15 heart malformed, abnormal
Prim-15 heart looping disrupted, abnormal
Long-pec brain malformed, abnormal
Long-pec brain development disrupted, abnormal
Long-pec digestive system malformed, abnormal
Long-pec digestive tract development disrupted, abnormal
Long-pec gut malformed, abnormal
Long-pec heart malformed, abnormal
Long-pec heart looping disrupted, abnormal
AB + MO2-ppm1k standard conditions Prim-5 apoptotic process increased occurrence, abnormal
twu34Tg + MO1-ppm1k standard conditions Prim-15 heart contraction decreased rate, abnormal
Full text @ Genes & Dev.