Fig. 4 mib2 knock-down in mibtfi91 embryos phenocopies mibta52b and mibm132. (A) her4 expression in (a–a″) control mibta52b, (b–b″) mib mRNA-injected mibta52b, and (c–c″) mib2 mRNA-injected mibta52b embryos at 22hpf; (a–c) head region, dorsal view; (a′–c′) trunk region, and (a″–c″) tail region around cloaca, both lateral view. (B) 3dpf tail pigmentation of (a) control mibta52b and (b) mib mRNA-injected mibta52b embryos, lateral view. (C–E) Phenotypic analysis in control or mib2-m3-injected mibtfi91 embryos. (C) islet-1 expression at 20ss, dorsal view; (D) her4 expression at 22hpf; (a–d) head region, dorsal view; (a′–d′) trunk region, lateral view and (E) 3dpf tail pigmentation, lateral view.
Reprinted from Developmental Biology, 305(1), Zhang, C., Li, Q., Lim, C.H., Qiu, X., and Jiang, Y.J., The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly, 14-27, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.