FIGURE

Fig. 3

ID

ZDB-FIG-070314-33

Publication

Songhet et al., 2007 - fgf1 is required for normal differentiation of erythrocytes in zebrafish primitive hematopoiesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

fgf1 morphants show altered gata1 and ika expression. Labeling of panels is as in Figure 2>. A-D: Early gata1 expression is normal in fgf1 morphants. E-H: Strong and persistent gata1-expressing cells in fgf1 morphants. Arrows point to the blood sinus covering the yolk, arrowheads to gata1-expressing cells in the intermediate cell mass (ICM) or elsewhere in the embryo. I-L: Close-ups and sections through the posterior ICM at 35 hours postfertilization (hpf; gata1). M,N:ika expression is normal in fgf1 morphants at 24 hpf. O,P: At 32 hpf, strong ika expression persists in fgf1 morphants, whereas it is down-regulated in control or wild-type embryos. Arrows/arrowheads as in E-H. Q-T: Cells strongly expressing ika accumulate in the ICM of fgf1 morphants. Close-ups and sections through the posterior ICM at 32 hpf. n, notochord

Expression Data

Genes:	gata1a ikzf1
Fish:	WT WT + MO1-fgf1a + MO2-fgf1a
Knockdown Reagents:	MO1-fgf1a MO2-fgf1a
Anatomical Terms:	blood intermediate cell mass of mesoderm
Stage Range:	14-19 somites to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-fgf1a + MO2-fgf1a
Knockdown Reagents:	MO1-fgf1a MO2-fgf1a
Observed In:	hemopoiesis intermediate cell mass of mesoderm
Stage Range:	Prim-15 to Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.