FIGURE

Fig. 2

ID

ZDB-FIG-070314-32

Publication

Songhet et al., 2007 - fgf1 is required for normal differentiation of erythrocytes in zebrafish primitive hematopoiesis

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Fig. 2

fgf1 morphants show accumulation of blood cells in the posterior intermediate cell mass (ICM), despite apparently normal vessel pattern and initially normal hematopoiesis. Stages are indicated bottom left, manipulation of embryos top right, and marker expression bottom right. A-D,G,H: Live embryos. Occasionally, fgf1 morphants have a kinked tail (arrowhead in B). Arrows in D point to accumulating cells in the ICM. E,F: The vessel marker kdra is normally expressed. G,H: Microangiography results in a grossly normal pattern of fgf1 morphants (rhodamine-dextran fluorescence of injected embryos, trunk, lateral view).

Expression Data

Gene:	kdrl
Fish:	WT WT + MO1-fgf1a + MO2-fgf1a
Knockdown Reagents:	MO1-fgf1a MO2-fgf1a
Anatomical Term:	blood vasculature
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-fgf1a + MO2-fgf1a
Knockdown Reagents:	MO1-fgf1a MO2-fgf1a
Observed In:	intermediate cell mass of mesoderm post-vent region post-vent vasculature
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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