FIGURE

Fig. 3

ID

ZDB-FIG-060918-2

Publication

Lecaudey et al., 2004 - The zebrafish Iroquois gene iro7 positions the r4/r5 boundary and controls neurogenesis in the rostral hindbrain

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Fig. 3

Knocking-down iro7 results in an anterior expansion of r5 at the expense of r4. (A-P) Whole-mount in situ hybridisation with the probes indicated (bottom left of each picture, colour coded) on embryos injected with Moz7 (A,C,E,G,I,K,M,O) or control embryos (B,D,F,H,J,L,N,P). Anterior is towards the left, except in E-H where anterior is towards the top. The inset in O presents a transverse section at the level of r4. The arrowheads indicate a group of cells expressing krx20 ectopically in the ventral part of r4. (C,D,K,L,M,N) Dorsal views of flat-mounted embryos. Stages are indicated at the bottom right of each picture. nc, neural crest.

Expression Data

Genes:	egr2b hoxb1a mafba
Fish:	WT WT + MO2-irx7
Knockdown Reagent:	MO2-irx7
Anatomical Terms:	neural plate presumptive rhombomere 3 presumptive rhombomere 4 presumptive rhombomere 5 presumptive rhombomere 6
Stage Range:	90%-epiboly to 5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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