FIGURE

Fig. 4

ID

ZDB-FIG-060606-1

Publication

Nica et al., 2006 - Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

eya1 is specifically required for the transcriptional activation of pit1 and six1. All panels show whole-mount in situ hybridizations of eya1 mutants (lower panels) and wild-type siblings (upper panels) with probes indicated in upper right corners and at stages indicated in lower right corners of lower panels. (A, D) Lateral views, anterior to the left, dorsal to the top; (B, C, E-I) ventral views, anterior to the left. Arrowhead in panel A points to anterior regions of the adenohypophyseal placode, arrow to posterior lateral regions, which most likely give rise to somatotropes and thyrotropes. Arrows in panel D point to the adenohypophyseal cells, some of which are located within the oral cavity of mutant. Scale bars are 50 μm.

Expression Data

Genes:	eya1 lhx3 pitx3 pou1f1 six1b
Fish:	WT eya1^tm90b/tm90b
Anatomical Terms:	adenohypophyseal placode adenohypophysis
Stage Range:	Prim-5 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 292(1), Nica, G., Herzog, W., Sonntag, C., Nowak, M., Schwarz, H., Zapata, A.G., Hammerschmidt, M., Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis, 189-204, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.