FIGURE

Fig. 6

ID

ZDB-FIG-060605-35

Publication

Hutchinson et al., 2006 - Islet1 and Islet2 have equivalent abilities to promote motoneuron formation and to specify motoneuron subtype identity

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Fig. 6

Formation of CaP subtype identity is independent of Islet2. (A,B) Embryos labeled with zn1 and znp1 Abs (green). Arrows indicate MiP axons, arrowheads indicate CaP axons. At 28 hpf, control embryos (A) have both CaP and MiP axons. Embryos misexpressing islet2 RNA (B) also have normal MiP and CaP axons. (C,D) Embryos labeled with zn1 and znp1 (green), and Islet (red) Abs. Arrowheads indicate CaP axons. CaP cell bodies (dots) co-label with Islet and zn1 Abs and project axons ventrally at 28 hpf in control embryos (C). islet2 MO-injected embryos (D) lack Islet staining in CaP cell bodies and have abnormal CaP axons. Scale bar: 20 µm.

Expression Data

Antibodies:	Ab2-isl zn-1 znp-1
Fish:	AB AB + MO1-isl2a
Knockdown Reagent:	MO1-isl2a
Anatomical Terms:	CaP motoneuron CaP motoneuron axon MiP motor neuron MiP motor neuron axon
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-isl2a
Knockdown Reagent:	MO1-isl2a
Observed In:	CaP motoneuron axon CaP motoneuron axon extension CaP motoneuron axon guidance
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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