FIGURE

Fig. 2

ID

ZDB-FIG-060301-17

Publication

Scholpp et al., 2006 - Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon

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Fig. 2

Mis-expression of shh results in an increase of the MDT. shh mRNA (150 pg) was injected into one of 32 cells to generate randomly distributed shh-positive cell clones, shown by an FITC-coupled lineage tracer (A-A''). Mis-expression of shh leads to expansion of ptc1 (B-C', bracket) and induces ptc1 positive clones at ectopic sites (arrows). dlx2a as well as lhx5 are expanded following shh mRNA mis-expression (D-G', bracket). dlx2a is induced anterior to the ZLI (white arrow), but not posterior (blue arrow). dbx1a and emx2 expression increases in size after shh mRNA mis-expression (H-K', brackets).

Expression Data

Genes:	dbx1a dlx2a emx2 lhx5 neurog1 ptch2 (all 6)
Fish:	WT
Anatomical Terms:	dorsal thalamus floor plate hypothalamus ventral thalamus zona limitans intrathalamica
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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