FIGURE

Fig. 4

ID
ZDB-FIG-050228-9
Publication
Norton et al., 2005 - Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones
Other Figures
(all 9)
All Figure Page
Back to All Figure Page
Fig. 4

Floorplate develops in mol-/- embryos independently of Hh activity. Lateral views (A,B), dorsal views (C-H) and transverse sections (I-R) of wild-type (A,C,E,G,I,K,M,O,Q) and mol-/- (B,D,F,H,J,L,N,P,R) embryos with (A,B,D,G,H) and without (C,E,F,I-R) cyclopamine treatment. (A,B) Both the wild-type and the mol-/- embryo treated with cyclopamine have cuboidally shaped floorplate cells (arrowhead) at 20 hpf. (C,D) Clutches of embryos from parents heterozygous for the moltv53a mutation. Treatment with cyclopamine between the 4-hour and 2-somite stages did not appear to affect expression of twhh in either wild-type or mol-/- mutants. (E-H) Wild-type and mol-/- embryos showing patchy ntn1 expression after treatment with cyclopamine. (I-R) Transverse sections through the spinal cord of wild-type and mol-/- embryos showing changes in floorplate expression of various genes in the mutants. cpm, cyclopamine.

Expression Data
Genes:
Fish:
Condition:
Anatomical Terms:
Stage Range: 1-4 somites to Prim-25

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.