FIGURE

Fig. 5

ID

ZDB-FIG-050228-10

Publication

Norton et al., 2005 - Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones

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Fig. 5

Floorplate differentiation fails in mol^-/- but not in smu^-/- embryos. Lateral (A-I) and dorsal (J-O) views of the trunk floorplate in 36 hpf (A-I) and 24 hpf (J-O) wild-type, mol^-/- and smu^-/- embryos. (A-O) Expression of floorplate differentiation markers col2a1, min1, min2, arx and ctgf is similar in wild-type and smu^-/- embryos but expression is severely reduced or absent in the mol^-/- embryos (despite the presence of floorplate cells, arrowhead in B). Although floorplate expression is retained, the somitic expression of arx and ctgf is lost in the smu^-/- mutants (L,O). fp, floorplate; hy, hypochord; nc, notochord.

Expression Data

Genes:	arxa col2a1a ccn2a spon2a spon2b
Fish:	WT foxa2^tv53a/tv53a smo^b641/b641 (AB)
Anatomical Terms:	floor plate hypochord notochord unspecified
Stage Range:	Prim-5 to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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