Gene

nkx2.2b

ID
ZDB-GENE-050217-3
Name
NK2 homeobox 2b
Symbol
nkx2.2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in floor plate formation and ventral spinal cord interneuron differentiation. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; prechordal plate; presumptive ectoderm; primary interneuron; and trunk. Orthologous to human NKX2-2 (NK2 homeobox 2).
Genome Resources
Note
None
Expression
All Expression Data
33 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nkx2.2b Human Ortholog
No data available
Associated With nkx2.2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:Q5BJA8 237
UniProtKB:Q5XX14 237
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations