Gene
nkx2.2b
- ID
- ZDB-GENE-050217-3
- Name
- NK2 homeobox 2b
- Symbol
- nkx2.2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within floor plate formation and ventral spinal cord interneuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; prechordal plate; presumptive ectoderm; primary interneuron; and trunk. Orthologous to human NKX2-2 (NK2 homeobox 2) and NKX2-8 (NK2 homeobox 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7162914 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q5BJA8 | InterPro | 237 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nkx2.2b-201
(1)
|
Ensembl | 1,634 nt |
Interactions and Pathways
No data available
Plasmids
No data available