ZFIN ID: ZDB-GENE-980526-437

Gene Name:no tail a
Gene Symbol: ntla

Previous Names: ZF-NTL(1) , wu:fc80a01(1) , ZF-T(1) , ntl, zft, T, brachyury, cb240(1) , id:ibd5074(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	284 figure(s) from 197 publications
Directly submitted expression data:	7 figure(s) (18 images) from Thisse et al., 2001 [cb240]
	1 figure(s) (2 images) from Kudoh et al., 2001 [ibd5074]
Wild Type Stages, Structures:	Blastula:128-cell (2.25h-2.50h) to Hatching:Long-pec (48.00h-60.00h)
	anterior axial hypoblast, axial chorda mesoderm ... (all 26)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   30 genotypes
Allele(s):   b160, b195, b459, b487, kt338 ... (all 13)

Phenotype: (current status)

Data:	12 figures from 6 publications
Observed in:	fin, Kupffers vesicle, mesoderm, notochord, notochord development ... (all 12)

Knockdown reagents: MO1-ntla (1) ,   MO2-ntla (1) ,   MO3-ntla (1) ,   MO4-ntla (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	convergent extension involved in axis elongation (more)
Cellular Component	nucleus (more)
Molecular Function	DNA binding (more)

All GO Terms (21)

Protein Families, Domains and Sites:

InterPro:IPR001699 (1) InterPro:IPR002070 (1) InterPro:IPR008967 (1) InterPro:IPR018186 (1)

PROSITE:PS01264 (1) PROSITE:PS01283 (1) PROSITE:PS50252 (1)

Pfam:PF00907 (1)

Gene Product Description

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ANTIBODIES:

Ab1-ntla (18)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

ntla Encodes

[EST] cb240 (1) , fc80a01 (1) , ibd5074 (1)    (order this) [cDNA] MGC:193897 (1)    (order this) , MGC:193903 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131162 (1)	2238 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:AB088068 (1)	4104 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl
Polypeptide	UniProtKB:Q07998 (1)	423 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:1468 (1)
All Sequence Information (18)

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OTHER  ntla  GENE / MARKER PAGES:

Entrez Gene:30399 (1)

Ensembl(Zv8):ENSDARG00000009905 (1)

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MAPPING INFORMATION:

LG:  19  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL	SU
Zebrafish	ntla	19
Human	T	6 (q27)	OMIM:601397 Entrez Gene:6862
Mouse	T	17 (4.02 cM)	MGI:98472 Entrez Gene:20997
Orthology Details

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CITATIONS   (407)