Research
General Information
ZIRC
ZFIN: Gene: dla
ZFIN ID: ZDB-GENE-980526-29

Gene Name:deltaA
Gene Symbol: dla
Previous Names: fa04c10, cb335(1) , wu:fa04c10(1) , delta A
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 49 figure(s) from 31 publications
Directly submitted expression data: 6 figure(s) (24 images) from Thisse et al., 2001 [cb335]
Wild Type Stages, Structures: Gastrula:Bud (10.00h-10.33h) to Adult (90d-730d, breeding adult)
  adenohypophyseal placode, basal plate midbrain region ... (all 40)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   11 genotypes
Allele(s):   b220, dx2, hi3499Tg, hi781Tg, hi840Tg
Phenotype: (current status)
  Data: 5 figures from 2 publications
  Observed in: axon, axon guidance, embryonic pattern specification, floor plate, hindbrain ... (all 9)
Knockdown reagents: MO1-dla (1) ,   MO2-dla (1) ,   MO3-dla (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process embryonic pattern specification (more)
Cellular Component integral to membrane (more)
Molecular Function protein binding (more)
All GO Terms (10)

Protein Families, Domains and Sites:
  • InterPro:IPR000152 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001774 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR006209 (1)
  • InterPro:IPR006210 (1)
  • InterPro:IPR011651 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR018097 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51051 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF01414 (1)
  • Pfam:PF07657 (1)
  • Loading Transcript Data...

    Gene Product Description


    ANTIBODIES:
    Ab1-dla (2), Ab1-dld (2)


    CONSTRUCTS WITH SEQUENCE FROM dla:
    Tg(dla:GFP)

    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    dla Contained in [BAC] CH211-133L11 (1)    (order this)
    dla Encodes [EST] cb335 (1)    (order this) , fa04c10 (1)
    [cDNA] cssl:d399 (1) , MGC:86576 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130954 (1) 3051 bp
    Genomic GenBank:AL929114 (1) 180158 bp
    Polypeptide UniProtKB:A1C3M9 (1) 772 aa
    Sequence Clusters UniGene:30326 (1)
    All Sequence Information (17)

    OTHER  dla  GENE / MARKER PAGES:

  • Entrez Gene:30131 (1)
  • VEGA:OTTDARG00000019396 (1)
  • Ensembl(Zv8):ENSDARG00000010791 (1)

  • MAPPING INFORMATION:
      LG:  1    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish dla  1
    Human DLL1  6 (q27)
  • Entrez Gene:28514
  • Mouse Dll1  17 (8.20 cM)
  • MGI:104659
  • Entrez Gene:13388
  • Orthology Details

    CITATIONS   (77)