Gene

tnksa

ID
ZDB-GENE-030131-7450
Name
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a
Symbol
tnksa Nomenclature History
Previous Names
  • TANK1 (1)
  • tnks1a (1)
  • tnks
  • wu:fj17h02
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have NAD+ ADP-ribosyltransferase activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; positive regulation of telomere capping; and protein localization to chromosome, telomeric region. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; dorsal telencephalon; hypothalamus; medulla oblongata; and preoptic area. Orthologous to human TNKS (tankyrase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wang et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Wang et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnksa Human Ortholog
No data available
Associated With tnksa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
Family IPR051165 Multifunctional Ankyrin Repeat Domain-Containing Protein
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain superfamily Multifunctional Ankyrin Repeat Domain-Containing Protein Poly(ADP-ribose) polymerase, catalytic domain Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M9PPY2 1026
UniProtKB:E9QD73 1252
UniProtKB:A0A8M3ALH5 1259
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tnks polyclonal Rabbit
  • IHC
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations