Gene
tnksa
- ID
- ZDB-GENE-030131-7450
- Name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a
- Symbol
- tnksa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have NAD+ ADP-ribosyltransferase activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; positive regulation of telomere capping; and protein localization to chromosome, telomeric region. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; dorsal telencephalon; hypothalamus; medulla oblongata; and preoptic area. Orthologous to human TNKS (tankyrase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wang et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001660 | Sterile alpha motif domain |
Domain | IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain |
Family | IPR051165 | Multifunctional Ankyrin Repeat Domain-Containing Protein |
Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Multifunctional Ankyrin Repeat Domain-Containing Protein | Poly(ADP-ribose) polymerase, catalytic domain | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PPY2
|
1026 | ||||||
UniProtKB:E9QD73
|
1252 | ||||||
UniProtKB:A0A8M3ALH5
|
1259 |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-tnks | polyclonal | Rabbit |
|
Santa Cruz Biotechnology, Inc.
|
2 |
Plasmids
No data available