Gene

tnksb

ID
ZDB-GENE-030131-4865
Name
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
Symbol
tnksb Nomenclature History
Previous Names
  • tnks1b (1)
  • fe02c12
  • si:ch211-155m12.3
  • wu:fe02c12
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable NAD+ ADP-ribosyltransferase activity. Acts upstream of or within glucose homeostasis. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; liver; optic cup; pleuroperitoneal region; and retina. Orthologous to human TNKS (tankyrase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Wang et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Wang et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnksb Human Ortholog
No data available
Associated With tnksb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
Domain IPR020683 Ankyrin repeat-containing domain
Family IPR028731 Poly [ADP-ribose] polymerase tankyrase-1
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily Poly(ADP-ribose) polymerase, catalytic domain Poly [ADP-ribose] polymerase tankyrase-1 Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily
UniProtKB:A3KGU1 1267
UniProtKB:A0A2R8QG67 1258
UniProtKB:A0A0R4IYN3 1274
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tnks polyclonal Rabbit
  • IHC
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations