Gene

tnksb

ID

ZDB-GENE-030131-4865

Name

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b

Symbol

tnksb Nomenclature History

Previous Names

tnks1b (1)
fe02c12
si:ch211-155m12.3
wu:fe02c12

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable NAD+ poly-ADP-ribosyltransferase activity. Acts upstream of or within glucose homeostasis. Predicted to be located in Golgi membrane and chromosome, telomeric region. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; liver; optic cup; pleuroperitoneal region; and retina. Orthologous to human TNKS (tankyrase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Wang et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Wang et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnksb Human Ortholog

No data available

Associated With tnksb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR012317	Poly(ADP-ribose) polymerase, catalytic domain
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat