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ZIRC
ZFIN ID: ZDB-GENE-030131-4865
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Gene Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
Gene Symbol: tnksb
Sequence Ontology ID : SO:0001217

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Previous Names: tnks1b (1), fe02c12, si:ch211-155m12.3, wu:fe02c12

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have NAD+ ADP-ribosyltransferase activity. Involved in glucose homeostasis. Predicted to localize to the cytoplasm and nucleus. Is expressed in brain; liver; optic cup; pleuroperitoneal  ...
GENE EXPRESSION
All Expression Data: 2 figures from Wang et al., 2015
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6961 Point Mutation Unknown Premature Stop ENU
sa13277 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa40363 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 4 figures from Wang et al., 2015
    Observed in:
    DISEASE ASSOCIATED WITH tnksb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tnksb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glucose homeostasis (more)
    Cellular Component cytoplasm (more)
    Molecular Function NAD+ ADP-ribosyltransferase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001660 (1)
  • InterPro:IPR002110 (1)
  • InterPro:IPR012317 (1)
  • InterPro:IPR013761 (1)
  • InterPro:IPR020683 (1)
  • InterPro:IPR028731 (1)
  • InterPro:IPR036770 (1)
  • PROSITE:PS50088 (1)
  • PROSITE:PS50105 (1)
  • PROSITE:PS50297 (1)
  • PROSITE:PS51059 (1)
  • Pfam:PF00023 (1)
  • Pfam:PF00644 (1)
  • Pfam:PF07647 (1)
  • Pfam:PF12796 (1)
  • Pfam:PF13606 (1)
  • EC:2.4.2.- (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tnksb-201 (1) 4216
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tnksb No data available
    MARKER RELATIONSHIPS
    tnksb Contained in: [BAC] CH211-155M12 (1) (order this)
    tnksb Encodes: [EST] fe02c12
    [cDNA] MGC:193847 (1), MGC:193858 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089415 (1) 3961 bp
    Select Tool
    Genomic GenBank:AL928901 (1) 145957 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IYN3 (1) 1274 aa
    Select Tool
    Sequence Clusters UniGene:80634 (1)
    Sequence Information (all 23)
    OTHER tnksb GENE PAGES
  • Alliance (1)
  • Gene:567533 (1)
  • VEGA:OTTDARG00000015800 (1)
  • Ensembl(GRCz11):ENSDARG00000062897 (2)
    • ORTHOLOGY for tnksb ( Chr: 5 )
    CITATIONS (16)