ZFIN ID: ZDB-GENE-030131-4865
Gene Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
Gene Symbol: tnksb    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: tnks1b (1), fe02c12, si:ch211-155m12.3, wu:fe02c12

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have NAD+ ADP-ribosyltransferase activity. Involved in glucose homeostasis. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; liver; optic cup; pleuroperitoneal region; and retina. Orthologous to human TNKS (tankyrase).
Genome Resources: Alliance (1),  Gene:567533 (1),  Ensembl(GRCz11):ENSDARG00000062897 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6961 Point Mutation Unknown Premature Stop ENU
sa13277 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40363 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tnksb N/A 1
    MO2-tnksb N/A 1
    DISEASE ASSOCIATED WITH tnksb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tnksb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glucose homeostasis (more)
    Cellular Component cytoplasm (more)
    Molecular Function NAD+ ADP-ribosyltransferase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tnksb-201 (1)    Ensembl 4216
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-tnks polyclonal Rabbit IHC Santa Cruz Biotechnology, Inc.
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tnksb No data available
    MARKER RELATIONSHIPS
    tnksb Contained in: [BAC] CH211-155M12 (1)
    tnksb Encodes: [EST] fe02c12
    [cDNA] MGC:193847 (1), MGC:193858 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001089415 (1) 3961 nt
    Genomic GenBank:AL928901 (1) 145957 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IYN3 (1) 1274 aa
    Sequence Information (all 22)
    ORTHOLOGY for tnksb ( Chr: 5 )
    CITATIONS (17)