ZFIN ID: ZDB-GENE-030131-7190

Gene Name:methyl CpG binding protein 2
Gene Symbol: mecp2

Previous Names: wu:fk96a04, zgc:111857
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	2 figure(s) from 2 publications
Directly submitted expression data:	1 figure(s) (1 images) from Thisse et al., 2004 [MGC:111857]
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Adult (90d-730d, breeding adult)
	unspecified, whole organism
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   3 genotypes
Allele(s):   fh232, unrec_mecp2

Phenotype: (current status)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Molecular Function	DNA binding
Cellular Component	nucleus

All GO Terms (2)

Protein Families, Domains and Sites:

InterPro:IPR001739 (1) InterPro:IPR016177 (1) InterPro:IPR017353 (1)

PROSITE:PS50982 (1)

Pfam:PF01429 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

mecp2 Contained in	[BAC] CH211-192F24 (1)    (order this) , DKEYP-77F7 (1)
mecp2 Encodes	[EST] fk96a04 [cDNA] MGC:111857 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_212736	1673 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX571687 (1)	173448 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q7T2T7 (1)	524 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:82151 (1)
All Sequence Information (13)

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OTHER  mecp2  GENE / MARKER PAGES:

Entrez Gene:335250 (1)

VEGA:OTTDARG00000020060 (1)

Ensembl(Zv8):ENSDARG00000014218 (1)

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MAPPING INFORMATION:

LG:  8    Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	mecp2	8
Human	MECP2	X (q28)	OMIM:300005 Entrez Gene:4204
Mouse	Mecp2	X (29.60 cM)	MGI:99918 Entrez Gene:17257
Orthology Details

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CITATIONS   (16)