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General Information
ZIRC
ZFIN: Gene: gbx1
ZFIN ID: ZDB-GENE-020117-2

Gene Name:gastrulation brain homeobox 1
Gene Symbol: gbx1
Previous Names: cb619(1) , wu:fj77a06(1) , fj77a06
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 26 figure(s) from 10 publications
Directly submitted expression data: 9 figure(s) (19 images) from Rhinn et al., 2003 [mb1]
  6 figure(s) (31 images) from Thisse et al., 2001 [cb619]
Wild Type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Hatching:Long-pec (48.00h-60.00h)
  blastoderm, cranial ganglion ... (all 23)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   2 genotypes
Allele(s):   fh271, unrec_gbx1
Phenotype: (current status)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Molecular Function DNA binding (more)
Biological Process regulation of cellular transcription (more)
Cellular Component nucleus
All GO Terms (7)

Protein Families, Domains and Sites:
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR012287 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    gbx1 Contained in [BAC] CH211-89L23 (1)    (order this)
    gbx1 Encodes [EST] cb619 (1)    (order this) , fj77a06 (1) , mb1 (1)
    [cDNA] MGC:194383 (1)    (order this) , MGC:194384 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_174861 (1) 1837 bp
    Genomic GenBank:CT583690 (1) 177248 bp
    Polypeptide UniProtKB:Q90ZB2 (1) 316 aa
    Sequence Clusters UniGene:81466 (1)
    All Sequence Information (15)

    OTHER  gbx1  GENE / MARKER PAGES:

  • Entrez Gene:142985 (1)
  • VEGA:OTTDARG00000028677 (1)
  • Ensembl(Zv8):ENSDARG00000071418 (1)

  • MAPPING INFORMATION:
      LG:  24  Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish gbx1  24
    Human GBX1  7 (q36)
  • OMIM:603354
  • Entrez Gene:2636
  • Mouse Gbx1  5 (15.00 cM)
  • MGI:95667
  • Entrez Gene:231044
  • Orthology Details

    CITATIONS   (29)