ZFIN is now using GRCz12tu for Genomic Data
Gene
lcp1
- ID
- ZDB-GENE-991213-5
- Name
- lymphocyte cytosolic protein 1 (L-plastin)
- Symbol
- lcp1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable actin filament binding activity and protein-macromolecule adaptor activity. Predicted to be involved in actin filament bundle assembly and actin filament network formation. Located in cytoplasm. Is expressed in several structures, including eye; hematopoietic cell; hematopoietic system; mesoderm; and renal system. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human LCP1 (lymphocyte cytosolic protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 236 figures from 178 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb245 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kell et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Conserved_site | IPR001589 | Actinin-type actin-binding domain, conserved site |
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR002048 | EF-hand domain |
| Family | IPR039959 | Fimbrin/Plastin |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Actinin-type actin-binding domain, conserved site | Calponin homology domain | CH domain superfamily | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Fimbrin/Plastin |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A140LGK1 | InterPro | 624 | |||||||
| UniProtKB:Q6P698 | InterPro | 624 | |||||||
| UniProtKB:A0AC58GD79 | InterPro | 624 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers