Gene

puf60b

ID

ZDB-GENE-040625-116

Name

poly-U binding splicing factor b

Symbol

puf60b Nomenclature History

Previous Names

fe37c05
si:ch211-12p8.2
si:zc12p8.2
wu:fb33e11
wu:fe37c05
zgc:86806 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have DNA binding activity and RNA binding activity. Predicted to be involved in RNA splicing; apoptotic process; and mRNA processing. Predicted to localize to nucleus. Is expressed in endocrine system; nervous system; pectoral fin; pharynx; and somite. Orthologous to human PUF60 (poly(U) binding splicing factor 60).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7142954 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With puf60b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Verheij syndrome	615583

Associated With puf60b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR003954	RNA recognition motif domain, eukaryote
Domain	IPR034209	PUF60, RNA recognition motif 1
Domain	IPR034211	PUF60, RNA recognition motif 2
Domain	IPR034212	PUF60, RNA recognition motif 3
Family	IPR006532	Poly-U binding splicing factor, PUF60-like
Family	IPR051974	Poly(U)-binding-splicing regulator
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	Poly-U binding splicing factor, PUF60-like	Poly(U)-binding-splicing regulator	PUF60, RNA recognition motif 1	PUF60, RNA recognition motif 2	PUF60, RNA recognition motif 3	RNA-binding domain superfamily	RNA recognition motif domain	RNA recognition motif domain, eukaryote
UniProtKB:Q6IQE0 InterPro	516
UniProtKB:A0A2R8RVR3 InterPro	520

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	puf60b-201 (1) Ensembl	Ensembl	2,136 nt	Select Tool
mRNA	puf60b-202 (1) Ensembl	Ensembl	2,041 nt	Select Tool ZFIN BLAST
mRNA	puf60b-203 (1) Ensembl	Ensembl	2,155 nt	Select Tool
mRNA	puf60b-204 (1) Ensembl	Ensembl	2,041 nt	Select Tool ZFIN BLAST
mRNA	puf60b-205 (1) Ensembl	Ensembl	867 nt	Select Tool
mRNA	puf60b-207 (1) Ensembl	Ensembl	854 nt	Select Tool
mRNA	puf60b-208 (1) Ensembl	Ensembl	529 nt	Select Tool
mRNA	puf60b-209 (1) Ensembl	Ensembl	1,658 nt	Select Tool ZFIN BLAST
ncRNA	puf60b-003 (1) Ensembl	Ensembl	548 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations