Gene
pus3
- ID
- ZDB-GENE-030131-9433
- Name
- pseudouridylate synthase 3
- Symbol
- pus3 Nomenclature History
- Previous Names
-
- fj78b12
- wu:fj78b12
- zgc:56653 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis and tRNA pseudouridine synthesis. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PUS3 (pseudouridine synthase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56653 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR020097 | Pseudouridine synthase I, TruA, alpha/beta domain |
| Family | IPR001406 | Pseudouridine synthase I, TruA |
| Family | IPR041707 | Pseudouridine synthase Pus3-like |
| Homologous_superfamily | IPR020094 | Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal |
| Homologous_superfamily | IPR020095 | Pseudouridine synthase I, TruA, C-terminal |
| Homologous_superfamily | IPR020103 | Pseudouridine synthase, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Length | Pseudouridine synthase, catalytic domain superfamily | Pseudouridine synthase I, TruA | Pseudouridine synthase I, TruA, alpha/beta domain | Pseudouridine synthase I, TruA, C-terminal | Pseudouridine synthase Pus3-like | Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZW97
|
460 |
Interactions and Pathways
No data available
Plasmids
No data available