ZFIN ID: ZDB-LAB-170210-3
Jie Mei Lab
PI/Director: Mei, Jie
Co-PI / Senior
He, Yan
Contact Person: Mei, Jie
Email: jmei@mail.hzau.edu.cn
Address: Laboratory of Genetic breeding and Devlopmental Biology College of Fisheries Huazhong Agricultural University No.1, Shizishan Street, Hongshan District Wuhan, Hubei 430070, China
Country: China
Phone: 86-27-87282113
Line Designation: hza

Show all 9 genomic features

We are interested in the genetic basis of sexual dimorphism and sex determination in fish species, also the maternal factors that regulate maternal mRNA degradation and zygotic gene activation in zebrafish.


Lu, X., He, Y., Liu, Y., Wang, X.P., Xue, Y.L., Zheng, Z.Y., Duan, S.Y., Kong, H.L., Zhang, R.Z., Huang, J.L., Deng, J., Duan, P. (2023) Intergenerational toxic effects of parental exposure to [Cn mim]NO3 (n = 2,4,6) on nervous and skeletal development in zebrafish offspring. Environmental toxicology. 38(9):2204-2218
Huang, P., Guo, W., Wang, Y., Xiong, Y., Ge, S., Gong, G., Lin, Q., Xu, Z., Gui, J.F., Mei, J. (2022) Genome-wide association study reveals the genetic basis of growth trait in yellow catfish with sexual size dimorphism. Genomics. 114(3):110380
Xiong, Y., Zheng, X., Ke, W., Gong, G., Wang, Y., Dan, C., Huang, P., Wu, J., Guo, W., Mei, J. (2020) Function and association analysis of Cyclophilin A gene with resistance to Edwardsiella ictaluri in yellow catfish. Developmental and comparative immunology. 113:103783
Xiong, S., Tian, J., Ge, S., Li, Z., Long, Z., Guo, W., Huang, P., He, Y., Xiao, T., Gui, J.F., Mei, J. (2020) The miRNA-200 cluster on chromosome 23 is required for oocyte maturation and ovulation in zebrafish. Biology of reproduction. 103(4):769-778
Ren, F., Lin, Q., Gong, G., Du, X., Dan, H., Qin, W., Miao, R., Xiong, Y., Xiao, R., Li, X., Gui, J.F., Mei, J. (2020) Igf2bp3 maintains maternal RNA stability and ensures early embryo development in zebrafish. Communications biology. 3:94
Mawed, S.A., He, Y., Zhang, J., Mei, J. (2020) Strategy of Hepatic Metabolic Defects Induced by beclin1 Heterozygosity in Adult Zebrafish. International Journal of Molecular Sciences. 21(4):
Huang, P., Xiong, S., Kang, J., Mei, J., Gui, J.F. (2018) Stat5b Regulates Sexually Dimorphic Gene Expression in Zebrafish Liver.. Frontiers in Physiology. 9:676
Xiong, S., Ma, W., Jing, J., Zhang, J., Dan, C., Gui, J.F., Mei, J. (2018) An miR-200 cluster on chromosome 23 regulates sperm motility in zebrafish. Endocrinology. 159(5):1982-1991
Guo, W., Xie, B., Xiong, S., Liang, X., Gui, J.F., Mei, J. (2017) miR-34a Regulates Sperm Motility in Zebrafish. International Journal of Molecular Sciences. 18(12)
Zhang, J., Zhang, X., Liu, Y., Su, Z., Dawar, F.U., Dan, H., He, Y., Gui, J.F., Mei, J. (2017) Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway. Oncotarget. 8:111807-111818
Xiong, S., Mei, J., Huang, P., Jing, J., Li, Z., Kang, J., Gui, J.F. (2017) Essential roles of stat5.1/stat5b in controlling fish somatic growth. Journal of genetics and genomics = Yi chuan xue bao. 44(12):577-585
Lin, Q., Mei, J., Li, Z., Zhang, X., Zhou, L., Gui, J.F. (2017) Distinct and Cooperative Roles of amh and dmrt1 in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish.. Genetics. 207(3):1007-1022
Lu, C., Wu, J., Xiong, S., Zhang, X., Zhang, J., Mei, J. (2017) MicroRNA-203a regulates fast muscle differentiation by targeting dmrt2a in zebrafish embryos. Gene. 625:49-54
He, Y., Huang, C.X., Chen, N., Wu, M., Huang, Y., Liu, H., Tang, R., Wang, W.M., Wang, H.L. (2017) The zebrafish miR-125c is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations and embryogenesis.. Oncotarget. 8:73846-73859
Huang, C.X., Chen, N., Wu, X.J., He, Y., Huang, C.H., Liu, H., Wang, W.M., Wang, H.L. (2017) Zebrafish let-7b acts downstream of hypoxia-inducible factor-1α to assist in hypoxia-mediated cell proliferation and cell cycle regulation. Life sciences. 171:21-29
Xiong, S., Wu, J, Jing, J., Huang, P., Li, Z., Mei, J., Gui, J.F, (2017) Loss of stat3 function leads to spine malformation and immune disorder in zebrafish. Science Bulletin. 62:Pages 185-196
Jing, J., Xiong, S., Li, Z., Wu, J., Zhou, L., Gui, J.F., Mei, J. (2015) A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish. Scientific Reports. 5:15906
Mei, J., Gui, J.F. (2015) Genetic basis and biotechnological manipulation of sexual dimorphism and sex determination in fish.. Science China. Life sciences. 58(2):124-36
Mei, J., Liu, S., Li, Z., and Gui, J.F. (2010) Mtmr8 is essential for vasculature development in zebrafish embryos. BMC Developmental Biology. 10:96
Mei, J., Li, Z., and Gui, J.F. (2009) Cooperation of Mtmr8 with PI3K regulates actin filament modeling and muscle development in zebrafish. PLoS One. 4(3):e4979
Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F. (2008) C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis. Developmental Biology. 319(2):273-284
Mei, J., and Gui, J. (2008) Bioinformatic identification of genes encoding C1q-domain-containing proteins in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 35(1):17-24