ZFIN Human Disease: osteosarcoma

OBO ID: DOID:3347

Term Name:	osteosarcoma		Search Ontology:
Synonyms:	bone tissue neoplasm Osteogenic sarcoma osteoid sarcoma Skeletal sarcoma
Definition:	A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). (2)
References:	GARD:7284 ICDO:9180/3 MESH:D012516 MESH:D018213 NCI:C9145 OMIM:259500 ORDO:668 SNOMEDCT_US_2023_03_01:189878003 UMLS_CUI:C0029463 UMLS_CUI:C0206639
Ontology:	Human Disease ( DOID:3347 )

Relationships

is a type of:	bone sarcoma bone sarcoma Show first 5 Terms
has subtype:	bone osteosarcoma childhood osteosarcoma chondroblastic osteosarcoma extraosseous osteosarcoma localized osteosarcoma ... Show All 6 Terms bone osteosarcoma childhood osteosarcoma chondroblastic osteosarcoma extraosseous osteosarcoma localized osteosarcoma metachronous osteosarcoma of the bone Show first 5 Terms

OTHER osteosarcoma PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
CHEK2	chek2	Osteosarcoma, somatic	259500
RB1	rb1	Osteosarcoma, somatic	259500
TP53	tp53	{Osteosarcoma}	259500

ZEBRAFISH MODELS

Fish	Conditions	Citations
WT	cancer xenotransplantation	Jin et al., 2020
mitfa^w2/w2; mpv17^a9/a9; y1Tg	cancer xenotransplantation	Mohseny et al., 2012

PHENOTYPE No data available

CITATIONS (9)