Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-236
Gene Name: retinal homeobox gene 1
Gene Symbol: rx1
Previous Name: etID309857.22 (1)
GENE EXPRESSION
All Expression Data: 33 figures from 27 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
  ciliary marginal zone, optic cup, optic primordium, optic vesicle (all 10) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-rx1 (1), MO2-rx1 (1), MO3-rx1 (1)
PHENOTYPE
Data: 5 figures from Nelson et al., 2009
Observed in: cell death, cell proliferation, Muller cell, neural retina development (all 10) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Microphthalmia, isolated 3 611038
GENE ONTOLOGY
Ontology GO Term
Biological Process camera-type eye photoreceptor cell differentiation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003654 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50803 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rx1-001 (1) 2884
    ncRNA rx1-002 (1) 938
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-rx1 (1)
    CONSTRUCTS WITH SEQUENCES FROM rx1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rx1 Contained in: [BAC] CH211-63J24 (1) (order this)
    rx1 Encodes: [cDNA] MGC:73026 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131225 (1) 2885 bp
    Genomic GenBank:CR936300 (1) 158446 bp
    Select Tool
    Polypeptide UniProtKB:O42356 (1) 330 aa
    Sequence Clusters UniGene:75761 (1)
    Sequence Information (all 12)
    OTHER rx1 GENE PAGES
  • Gene:30472 (1)
  • VEGA:OTTDARG00000017768 (1)
  • Ensembl(Zv9):ENSDARG00000071684 (1)
  • MAPPING INFORMATION
    Chr: 22 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish rx1 22  
    Human RAX 18 (18q21.32)
  • OMIM:601881
  • Gene:30062
  • Mouse Rax 18 ( 39.03 cM)
  • MGI:109632
  • Gene:19434
  • CITATIONS (64)