ZFIN ID: ZDB-GENE-990415-236
Gene Name: retinal homeobox gene 1
Gene Symbol: rx1
Previous Name: etID309857.22 (1)
Location: Chr: 22 Mapping Details/Browsers
GENE EXPRESSION
All Expression Data: 44 figures from 34 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  ciliary marginal zone, eye, optic cup, optic primordium (all 14) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Targeting reagents: MO1-rx1 (1), MO2-rx1 (1), MO3-rx1 (1)
PHENOTYPE
Data: 5 figures from Nelson et al., 2009
Observed in: cell death, cell proliferation, Muller cell, neural retina development (all 10) expand
DISEASE ASSOCIATED WITH rx1 HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
microphthalmia Microphthalmia, isolated 3 611038
GENE ONTOLOGY 
Ontology GO Term
Biological Process camera-type eye photoreceptor cell differentiation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003654 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50803 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rx1-001 (1) 2884
    ncRNA rx1-002 (1) 938
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    Ab1-rx1 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rx1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    rx1Contained in: [BAC] CH211-63J24 (1) (order this)
    rx1Encodes: [cDNA] MGC:73026 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131225 (1) 2885bp
    Genomic GenBank:CR936300 (1) 158446bp
    Select Tool
    Polypeptide UniProtKB:O42356 (1) 330aa
    Sequence Clusters UniGene:75761 (1)
    Sequence Information (all 12)
    OTHER rx1 GENE PAGES 
  • Gene:30472 (1)
  • VEGA:OTTDARG00000017768 (1)
  • Ensembl(GRCz10):ENSDARG00000071684 (1)
  • ORTHOLOGY for rx1 (Chr: 22) 
    Species Symbol Chromosome Accession # Evidence
    Human RAX 18
  • Gene:30062
  • OMIM:601881
  • HGNC:18662
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Rax 18
  • MGI:109632
  • Gene:19434
  • Amino acid sequence comparison (2)
    Download Curated Orthology
    CITATIONS (75)