Gene

myo1cb

ID

ZDB-GENE-090429-3

Name

myosin Ic, paralog b

Symbol

myo1cb Nomenclature History

Previous Names

myo1c
fj81f11
wu:fj81f11

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable actin filament binding activity and microfilament motor activity. Acts upstream of or within glomerulus development. Predicted to be part of myosin complex. Predicted to be active in several cellular components, including actin cytoskeleton; microvillus; and vesicle. Is expressed in several structures, including digestive system; head; notochord; pectoral fin; and pronephric glomerulus. Orthologous to human MYO1C (myosin IC).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Arif et al., 2013

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myo1cb Human Ortholog

No data available

Associated With myo1cb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000048	IQ motif, EF-hand binding site
Domain	IPR001609	Myosin head, motor domain-like
Domain	IPR010926	Class I myosin tail homology domain
Domain	IPR036072	Class I myosin, motor domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	Class I myosin, motor domain	Class I myosin tail homology domain	IQ motif, EF-hand binding site	Kinesin motor domain superfamily	Myosin head, motor domain-like	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M3APY8 InterPro	1028
UniProtKB:A0A2R8Q9G7 InterPro	1068
UniProtKB:E7F5R7 InterPro	1043
UniProtKB:A0A286Y9H2 InterPro	1069

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	myo1cb-201 (1) Ensembl	Ensembl	3,132 nt	Select Tool ZFIN BLAST
mRNA	myo1cb-202 (1) Ensembl	Ensembl	679 nt	Select Tool ZFIN BLAST
mRNA	myo1cb-203 (1) Ensembl	Ensembl	6,430 nt	Select Tool ZFIN BLAST
mRNA	myo1cb-204 (1) Ensembl	Ensembl	3,210 nt	Select Tool ZFIN BLAST
mRNA	myo1cb-205 (1) Ensembl	Ensembl	4,623 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-myo1c	monoclonal	myo1ca myo1cb		Mouse			2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations