ZFIN ID: ZDB-GENE-090429-3
Gene Name: myosin Ic, paralog b
Gene Symbol: myo1cb    Nomenclature History

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Previous Names: myo1c, fj81f11, wu:fj81f11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin binding activity; and motor activity. Involved in glomerulus development. Predicted to localize to the myosin complex. Is expressed in several structures, including digestive system; head; notochord; pectoral fin; and pronephric glomerulus. Orthologous to human MYO1C (myosin IC).
Genome Resources: Alliance (1),  Gene:566459 (1),  Ensembl(GRCz11):ENSDARG00000061579 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7408 Point Mutation Unknown Missense ENU
sa12270 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16637 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22660 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35902 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44824 Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myo1cb N/A 1
    MO2-myo1cb N/A 1
    DISEASE ASSOCIATED WITH myo1cb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH myo1cb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glomerulus development (more)
    Cellular Component myosin complex (more)
    Molecular Function actin binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Binding_site IPR000048 IQ motif, EF-hand binding site
    Domain IPR001609 Myosin head, motor domain
    Domain IPR010926 Class I myosin tail homology domain
    Domain IPR036072 Class I myosin, motor domain
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    Homologous_superfamily IPR036961 Kinesin motor domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myo1cb-202 (1)    Ensembl 679
    myo1cb-203 (1)    Ensembl 6430
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-myo1c monoclonal Mouse 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myo1cb No data available
    MARKER RELATIONSHIPS
    myo1cb Contained in: [BAC] CH211-209M4 (1), DKEY-118K5 (order this)
    myo1cb Encodes: [EST] fj81f11
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001317189 (1)
    Genomic GenBank:CR522882 (1) 129430 nt
    Select Tool
    Polypeptide UniProtKB:A0A286Y9H2 (1) 1069 aa
    Sequence Information (all 21)
    ORTHOLOGY for myo1cb ( Chr: 15 )
    CITATIONS (24)