Gene

bcar3

ID
ZDB-GENE-080513-4
Name
BCAR3 adaptor protein, NSP family member
Symbol
bcar3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Orthologous to human BCAR3 (BCAR3 adaptor protein, NSP family member).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bcar3 Human Ortholog
No data available
Associated With bcar3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001660 Sterile alpha motif domain
Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
Domain IPR044102 SHEP1/BCAR3/NSP1, SH2 domain
Family IPR051853 Adapter protein with SH2 and Ras-GEF domains
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR023578 Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Homologous_superfamily IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamily
Domain Details Per Protein
Protein Length Adapter protein with SH2 and Ras-GEF domains Ras guanine-nucleotide exchange factor, catalytic domain superfamily Ras guanine nucleotide exchange factor domain superfamily Ras guanine-nucleotide exchange factors catalytic domain SH2 domain SH2 domain superfamily SHEP1/BCAR3/NSP1, SH2 domain Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M3BBM9 756
UniProtKB:F1R3Z4 918
UniProtKB:A0A8M2BEX1 912
UniProtKB:A0A8M9QDU4 727
UniProtKB:B0UXN8 746
UniProtKB:A0A8M2BED0 841
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bcar3-201 (1) Ensembl 2,796 nt
mRNA bcar3-202 (1) Ensembl 655 nt
mRNA bcar3-203 (1) Ensembl 2,693 nt
mRNA bcar3-204 (1) Ensembl 537 nt
mRNA bcar3-205 (1) Ensembl 2,390 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations