Gene
traf1
- ID
- ZDB-GENE-071120-4
- Name
- TNF receptor-associated factor 1
- Symbol
- traf1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have tumor necrosis factor receptor binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to cytoplasmic side of plasma membrane. Orthologous to human TRAF1 (TNF receptor associated factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001293 | Zinc finger, TRAF-type |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR002083 | MATH/TRAF domain |
| Domain | IPR032070 | TNF receptor-associated factor, BIRC3 binding domain |
| Domain | IPR037306 | TNF receptor-associated factor 1, MATH domain |
| Domain | IPR049342 | TRAF1-6, MATH domain |
| Family | IPR012227 | TNF receptor-associated factor TRAF, metazoa |
| Homologous_superfamily | IPR008974 | TRAF-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | MATH/TRAF domain | TNF receptor-associated factor 1, MATH domain | TNF receptor-associated factor, BIRC3 binding domain | TNF receptor-associated factor TRAF, metazoa | TRAF1-6, MATH domain | TRAF-like | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, TRAF-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B0UXK1
|
551 |
Interactions and Pathways
No data available
Plasmids
No data available