Gene
traf1
- ID
- ZDB-GENE-071120-4
- Name
- TNF receptor-associated factor 1
- Symbol
- traf1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable signaling adaptor activity and tumor necrosis factor receptor binding activity. Predicted to be involved in regulation of canonical NF-kappaB signal transduction and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within regulation of apoptotic process and signal transduction. Predicted to be active in cytoplasm. Orthologous to human TRAF1 (TNF receptor associated factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001293 | Zinc finger, TRAF-type |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR002083 | MATH/TRAF domain |
| Domain | IPR032070 | TNF receptor-associated factor, BIRC3 binding domain |
| Domain | IPR037306 | TNF receptor-associated factor 1, MATH domain |
| Domain | IPR049342 | TRAF1-6, MATH domain |
| Family | IPR012227 | TNF receptor-associated factor TRAF, metazoa |
| Homologous_superfamily | IPR008974 | TRAF-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | MATH/TRAF domain | TNF receptor-associated factor 1, MATH domain | TNF receptor-associated factor, BIRC3 binding domain | TNF receptor-associated factor TRAF, metazoa | TRAF1-6, MATH domain | TRAF-like | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, TRAF-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B0UXK1
|
551 |
Interactions and Pathways
No data available
Plasmids
No data available