ZFIN ID: ZDB-GENE-041114-63
Gene Name: nuclear receptor subfamily 2, group E, member 3
Gene Symbol: nr2e3
Previous Names: NR2D2 (1), PNR (1), fj55b07, wu:fj55b07, zgc:103631
Location: Chr: 25   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 30 figures from 14 publications
Directly Submitted Expression Data: 8 figures (26 images) from Thisse et al., 2008 [MGC:103631]
  7 figures (20 images) from Thisse et al., 2004 [MGC:103631]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
  diencephalon, epiphysis, optic vesicle, pineal complex (all 12) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 genotypes
Alleles: fh342, fh343, nr2e3_unrecovered, sa15662
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Enhanced S-cone syndrome 268100
Retinitis pigmentosa 37 611131
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000536 (1)
  • InterPro:IPR001628 (1)
  • InterPro:IPR001723 (1)
  • InterPro:IPR003068 (1)
  • InterPro:IPR008946 (1)
  • InterPro:IPR013088 (1)
  • PROSITE:PS00031 (1)
  • PROSITE:PS51030 (1)
  • Pfam:PF00104 (1)
  • Pfam:PF00105 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nr2e3-001 (1) 2072
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-nr2e3 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nr2e3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nr2e3 Contained in: [BAC] DKEYP-91C1 (1)
    nr2e3 Encodes: [EST] fj55b07
    [cDNA] MGC:103631 (1) (order this), MGC:173759 (1) (order this), MGC:191964 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007368 (1) 2079 bp
    Genomic GenBank:AL929050 (1) 196743 bp
    Select Tool
    Polypeptide UniProtKB:F1QGF3 (1) 426 aa
    Sequence Clusters UniGene:81177 (1)
    Sequence Information (all 23)
    OTHER nr2e3 GENE PAGES
  • Gene:492496 (1)
  • VEGA:OTTDARG00000022455 (1)
  • Ensembl(Zv9):ENSDARG00000045904 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish nr2e3 25  
    Human NR2E3 15 (15q23)
  • OMIM:604485
  • Gene:10002
  • Mouse Nr2e3 9 ( 32.35 cM)
  • MGI:1346317
  • Gene:23958
  • Orthology Details
    CITATIONS (31)