ZFIN ID: ZDB-GENE-041114-63
Gene Name: nuclear receptor subfamily 2, group E, member 3
Gene Symbol: nr2e3

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Previous Names: NR2D2 (1), fj55b07, PNR (1), wu:fj55b07, zgc:103631

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 35 figures from 16 publications
Directly Submitted Expression Data: 8 figures (26 images) from Thisse et al., 2008 [MGC:103631]
  7 figures (20 images) from Thisse et al., 2004 [MGC:103631]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
  diencephalon, epiphysis, optic vesicle, pineal complex (all 15) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh342 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh343 Point Mutation Unknown Unknown ENU
    nr2e3_unrecovered Point Mutation Unknown Unknown ENU
    sa15662 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30255 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-nr2e3 (1), MO2-nr2e3 (1)
    PHENOTYPE
    Data: 2 figures from Khuansuwan et al., 2016
    Observed in: parapineal organ neuron, parapineal organ neuron fate specification, parapineal organ, pineal complex photoreceptor cell (all 6) expand
    DISEASE ASSOCIATED WITH nr2e3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    retinitis pigmentosa 37 Retinitis pigmentosa 37 611131
    Enhanced S-cone syndrome 268100
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pineal gland development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000536 (1)
  • InterPro:IPR001628 (1)
  • InterPro:IPR001723 (1)
  • InterPro:IPR003068 (1)
  • InterPro:IPR013088 (1)
  • PROSITE:PS00031 (1)
  • PROSITE:PS51030 (1)
  • Pfam:PF00104 (1)
  • Pfam:PF00105 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nr2e3-001 (1) 2072
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab1-nr2e3 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nr2e3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nr2e3Contained in: [BAC] DKEYP-91C1 (1)
    nr2e3Encodes: [EST] fj55b07
    [cDNA] MGC:103631 (1) (order this), MGC:173759 (1) (order this), MGC:191964 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007368 (1) 2079bp
    Genomic GenBank:AL929050 (1) 196743bp
    Select Tool
    Polypeptide UniProtKB:F1QGF3 (1) 426aa
    Sequence Clusters UniGene:81177 (1)
    Sequence Information (all 23)
    OTHER nr2e3 GENE PAGES
  • Gene:492496 (1)
  • VEGA:OTTDARG00000022455 (1)
  • Ensembl(GRCz10):ENSDARG00000045904 (1)
  • ORTHOLOGY for nr2e3 (Chr: 25)
    Species Symbol Chromosome Accession # Evidence
    Human NR2E3 15
  • Gene:10002
  • OMIM:604485
  • HGNC:7974
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (1)
    Phylogenetic tree (1)
    Mouse Nr2e3 9
  • MGI:1346317
  • Gene:23958
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (1)
    Phylogenetic tree (1)
    Download Curated Orthology
    CITATIONS (37)