Gene
bin1b
- ID
- ZDB-GENE-030425-1
- Name
- bridging integrator 1b
- Symbol
- bin1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have phospholipid binding activity and tau protein binding activity. Involved in cardiac muscle contraction. Predicted to localize to plasma membrane and synaptic vesicle. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Is expressed in adaxial cell; cardiovascular system; musculature system; and somite. Orthologous to human BIN1 (bridging integrator 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb57 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Hong et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
centronuclear myopathy 2 | Alliance | Centronuclear myopathy 2 | 255200 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | AH/BAR domain superfamily | Amphiphysin | Amphiphysin 2, SH3 domain | BAR domain | SH3 domain | SH3-like domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3AT31
|
543 | ||||||
UniProtKB:A0A8M3B348
|
533 | ||||||
UniProtKB:A0A8M9QFB8
|
407 | ||||||
UniProtKB:A0A8M9QAA8
|
396 | ||||||
UniProtKB:A0A8M3AT25
|
564 | ||||||
UniProtKB:A0A8M3B066
|
451 | ||||||
UniProtKB:A0A8M3BA55
|
545 | ||||||
UniProtKB:A0A2R8QMI5
|
576 | ||||||
UniProtKB:F1QRX4
|
364 | ||||||
UniProtKB:A0A8M3B064
|
565 | ||||||
UniProtKB:A0A8M3AT30
|
440 | ||||||
UniProtKB:A0A8M9PZM7
|
568 |
Interactions and Pathways
No data available
Plasmids