Gene
ddx18
- ID
- ZDB-GENE-030131-9685
- Name
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
- Symbol
- ddx18 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; RNA binding activity; and RNA helicase activity. Involved in myeloid cell differentiation. Predicted to localize to nucleolus. Is expressed in several structures, including alar plate midbrain region; digestive system; intermediate cell mass of mesoderm; nervous system; and trunk vasculature. Orthologous to human DDX18 (DEAD-box helicase 18).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb155 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR000629 | ATP-dependent RNA helicase DEAD-box, conserved site |
Domain | IPR001650 | Helicase, C-terminal domain-like |
Domain | IPR011545 | DEAD/DEAH box helicase domain |
Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
Domain | IPR025313 | ATP-dependent rRNA helicase SPB4-like, C-terminal extension |
Domain | IPR044773 | DDX18/Has1, DEAD-box helicase domain |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | ATP-dependent RNA helicase DEAD-box, conserved site | ATP-dependent rRNA helicase SPB4-like, C-terminal extension | DDX18/Has1, DEAD-box helicase domain | DEAD/DEAH box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|---|---|
UniProtKB:Q6DRL1
|
653 |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-ddx18 | polyclonal | IgG | Rabbit |
|
Bethyl Laboratories, Inc.
|
2 |
Plasmids
No data available